Acute Promyelocytic Leukima in Pregnancy Presenting as DIC - A Case Report and Review of Literature

  • Lakshmi R Pillai DNB Resident, Department of obstetrics and gynecology, BMH, Calicut
  • Rabiyabi B
  • Shinto Francis Thekkudan
  • Anoop Kumar

Abstract

Acute promyelocytic leukemia is a unique subset of acute myeloid leukemias characterised by the proliferation of neoplastic promyelocytes bearing chromosomal translocation t (15;17). Although APML accounts for nearly 13% of acute myeloblastic leukemia cases, it usually affects young adults and hence increasing the possibility of its occurrence during pregnancy. But to arrive at a diagnosis of leukemia in pregnancy, one should need a high index of suspicion. As most cases of acute promyelocytic leukemia present with coagulopathy, a peripheral smear study in pregnant women with similar picture can help in timely diagnosis and appropriate management. Here we discuss the case of a pregnant lady who had been diagnosed with APML in pregnancy in the second trimester and her clinical outcome.
Published
2024-01-19
How to Cite
PILLAI, Lakshmi R et al. Acute Promyelocytic Leukima in Pregnancy Presenting as DIC - A Case Report and Review of Literature. BMH Medical Journal - ISSN 2348–392X, [S.l.], v. 11, n. 2, p. 19-24, jan. 2024. ISSN 2348-392X. Available at: <https://www.babymhospital.org/BMH_MJ/index.php/BMHMJ/article/view/379>. Date accessed: 29 may 2024.
Section
Case Reports